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Hi, Brady. I have the same question. usually, I extracted the value for each ROI into SPSS and do further analysis. But sometimes the extracted ROI based on group analysis was not significant in SPSS. I was confused about whether there is better solution.

At 2019-03-21 01:48:34, "Williamson, Brady" Brady.Williamson@cchmc.org wrote:

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Hi,

I have a couple of specific questions about mri_glmfit that I could not quite find the answers to in the tutorials or message boards.

How would I run mri_glmfit in a custom ROI (or set of ROIs) and then correct for multiple comparisons? I have found information on how to use the freesurfer predefined labels but not a custom regions. Just for some background, I have a set of 50 regions that make up our network of interest and I would like to limit the glm to these regions. How do I extract and use the results from a whole-brain glm, above a specified corrected threshold, and use those in subsequent analyses? I am doing a whole-brain, between groups analysis and then trying to use the significant results from that in within-subjects analyses.

Thank you very much for your time,

Brady