Hi:

Thanks for the reply! Attached is the image.

Regards, Hock Wei SOON

-----Original Message----- From: Bruce Fischl [mailto:fischl@nmr.mgh.harvard.edu] Sent: Monday, September 27, 2010 11:49 PM To: Soon Hock Wei Cc: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Pial Edit on Atrophied Brain

could you send us an image to illustrate what you mean? On Mon, 27 Sep 2010, Soon Hock Wei wrote:

Dear All:   I am working on MRI images of subjects suffered from dementia. In severe cases, atrophy is observed where the white matter loss causes reduced white/gray differentiation. Hence, the pial surface generated from the autorecon2 does not include what is clearly atrophied cortical tissue without the underlying white matter.   I could not find any way to manually correct for this pial surface (i.e. to expand the surface outward to include the atrophied cortical tissue). The nearest wm surface is far away due to white matter loss. Can anyone please give me some advices?   Any suggestion is appreciated.   Regards, Hock Wei SOON

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