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 Besides patching the python distribution, another option available now is the development arm64 build for silicon Macs with an M1, M2 processor.  But this is not a release build and so has not been tested like a stable release.  The dev builds are currently ~3 months post the 7.4.1 release from back in June of this. year.  We’d be happy to hear how it goes if you try it.  The download links are below. - R.https://secure-web.cisco.com/1aFiKh6YzbcJ_9V-mQth29TZB1SeCRdpmUdrLhAH6aMSmX5... https://secure-web.cisco.com/1M-Y1AHK0ybK-HgTbS6EGioPOtjnLKD9oxxiz5O9fG-v6vk...

On Sep 26, 2023, at 18:01, Sorby-Adams, Annabel <ASORBY-ADAMS@mgh.harvard.edu> wrote:        External Email - Use Caution        Hi Julian, I have managed to run recon-all on my Apple M1 macOS Ventura using the 7.3.2 version of Freesurfer. It does not work on 7.4.2 or dev versions, however. These instructions were posted in a previous correspondence from fsbuild, but reposting here for anyone else having the same issue:  You may not be able to run these commands without sudo/admin permissions on your machine.1) Download the tensorflow-2.4.1-py3-none-any.whl from,MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to behttps://drive.google.com/file/d/15Qeve5FIA137KON67ehKIOyXy1N0PbAC/view?usp=s...) Check the download is OK with the md5 command in the terminal window,$ md5 tensorflow-2.4.1-py3-none-any.whlMD5 (tensorflow-2.4.1-py3-none-any.whl) = fab44de8702faf65e17a22d706a525a4DO NOT PROCEED UNTIL YOU GET THE ABOVE OUTPUT FROM the md5 command.3) Setup the Freesurfer 7.3.2 environment (shown here as installed via .pkg file under /Applications) and verify the path to fspython is from the 7.3.2 release,$ export FREESURFER_HOME=/Applications/freesurfer/7.3.2$ source $FREESURFER_HOME/SetUpFreeSurfer.sh-------- freesurfer-darwin-macOS-7.3.2-20220803-878457d --------... environment variable settings output ...$ which fspython/Applications/freesurfer/7.3.2/bin/fspython4) Uninstall the existing tensorflow package with,$ sudo $FREESURFER_HOME/python/bin/python3 -m pip uninstall tensorflow... apart from any warnings you should see the output ...Successfully uninstalled tensorflow-2.4.15) Install the package downloaded above.  This command assumes the package is in the current directory where the command is run.$ sudo -H $FREESURFER_HOME/python/bin/python3 -m pip install ./tensorflow-2.4.1-py3-none-any.whl... apart from warnings and output about requirements (which should all be satisfied) ...... you should see tensorflow was updated ....Successfully installed tensorflow-2.4.1CHECK THE UPDATE:$ which fspython/Applications/freesurfer/7.3.2/bin/fspython$ fspython>>> import sys, os>>> import tensorflow>>>You should see the prompt return to ">>>" after the import of tensorflow with no errors reported.  Hit Ctrl-D to escape the python session.  The update should now be complete. Once you have done this you should be able to run recon-all via 7.3.2. Hope this works!Annabel From: freesurfer-bounces@nmr.mgh.harvard.edu <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Iglesias Gonzalez, Juan E. <JIGLESIASGONZALEZ@mgh.harvard.edu>Date: Tuesday, 26 September 2023 at 17:35To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>Subject: Re: [Freesurfer] Recon-all-clinical error: Illegal instruction Error in SynthSeg        External Email - Use Caution        Dear Julian,I believe this is a problem with SynthSeg not being compatible with the new microprocessor in MAC computers. Our software engineers are looking into solutions to this.Sorry for the inconvenience,Eugenio --Juan Eugenio Iglesiashttp://http://secure-web.cisco.com/1DgebDH1WCLKceFhMcyIutLihRRkTXmu8dVOr_f4V... <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Conrad, Julian <Julian.Conrad@medma.uni-heidelberg.de>Date: Tuesday, September 26, 2023 at 4:38 PMTo: freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>Subject: [Freesurfer] Recon-all-clinical error: Illegal instruction Error in SynthSeg        External Email - Use Caution        Hello FreeSurfer Developers, I'm attempting to  do a surface reconstruction from a GRE magnitude image using recon-all-clinical.shWhen I am running the pipeline, I get the following error: Illegal instructionError in SynthSeg neuroadmin@medma0236 ~ % recon-all-clinical.sh /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/RC026_sub-10_ses-mri01_part-mag.nii RC026_sub-010_ses-mri01 8 /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/freesurfer#--------------------------------------------#@# recon-all-clinical Di 26 Sep 2023 21:53:31 CEST mri_convert /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/RC026_sub-10_ses-mri01_part-mag.nii /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/freesurfer/RC026_sub-010_ses-mri01/mri/native.mgz reading from /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/RC026_sub-10_ses-mri01_part-mag.nii...TR=49.00, TE=0.00, TI=0.00, flip angle=0.00i_ras = (0.997386, 0.00125151, 0.0722456)j_ras = (2.37011e-10, 0.99985, -0.0173204)k_ras = (-0.0722564, 0.0172751, 0.997236)writing to /Users/neuroadmin/Daten/UMM/ALS/Nifti/RC026_sub-010/ses-mri01/anat/freesurfer/RC026_sub-010_ses-mri01/mri/native.mgz... Illegal instruction Error in SynthSeg 1) FreeSurfer version: freesurfer-macOS-darwin_x86_64-7.4.12) Platform: MacOS X Darwin Hope this information is sufficient and there is an easy solution.Best regards,Julian _______________________________________________Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer