Dear Dr. Yendiki,

Thank you very much for your quick response. To calculate the weighted DTI measure, per your previous emails, we would need to normalize path.pd.nii.gz, right? If this is the case, we could use the following equation correct for weighted measurement:

dti_para (DTI parameter image) path_pd (path.pd.nii.gz)

sum(dti_para.*path_pd))/sum(path_pd)

Thank you very much.

Minjie

On Thu, Jun 28, 2012 at 11:05 AM, Anastasia Yendiki ayendiki@nmr.mgh.harvard.edu wrote:

Hi Minjie - These commonly used measures are provided for your convenience. You can always use the reconstructed path distribution volume path.pd.nii.gz, thresholded or not, as a mask to average your measurement of choice.

a.y

On Thu, 28 Jun 2012, Minjie Wu wrote:

...

Dear TRACULA Developer & User,

I am wondering if it is possible to add other DTI measurements to the pathstats.overall.txt along with those DTI parameters already included (FA, MD, AD, RD)?

Thank you very much. Minjie _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.

Thank you very much. We would like to do the weighted measure, as we believe it would be more sensitive and robust to WM abnormalities in our patient population.

Minjie

On Thu, Jun 28, 2012 at 11:52 AM, Anastasia Yendiki ayendiki@nmr.mgh.harvard.edu wrote:

Yes, if you wanted to do a weighted average of your measure. Or you could just theshold and binarize path.pd and use it a simple ROI to do an unweighted average.

On Thu, 28 Jun 2012, Minjie Wu wrote:

...

Dear Dr. Yendiki,

Thank you very much for your quick response. To calculate the weighted DTI measure, per your previous emails, we would need to normalize path.pd.nii.gz, right? If this is the case, we could use the following equation correct for weighted measurement:

dti_para (DTI parameter image) path_pd (path.pd.nii.gz)

sum(dti_para.*path_pd))/sum(path_pd)

Thank you very much.

Minjie

On Thu, Jun 28, 2012 at 11:05 AM, Anastasia Yendiki ayendiki@nmr.mgh.harvard.edu wrote:

...

Hi Minjie - These commonly used measures are provided for your convenience. You can always use the reconstructed path distribution volume path.pd.nii.gz, thresholded or not, as a mask to average your measurement of choice.

a.y

On Thu, 28 Jun 2012, Minjie Wu wrote:

...

Dear TRACULA Developer & User,

I am wondering if it is possible to add other DTI measurements to the pathstats.overall.txt along with those DTI parameters already included (FA, MD, AD, RD)?

Thank you very much. Minjie _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.