Hi Michele,

simply google: "Longitudinal FreeSurfer" or klick: http://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalProcessing

There is a step by step description on the longitudinal stream. It basically means: 1. to process your two time points individually through freesurfer (standard processing). 2. to create a template for each subjects from these processed time points 3. to run the two time points again (passing it the template) to compute better longitudinal results (less variability, more accuracy).

Best, Martin

On Tue, 2010-06-29 at 10:25 -0400, Bruce Fischl wrote:

Hi Michele,

that is a longitudinal analysis. Martin Reuter (ccd) can point you in the right direction.

thanks Bruce On Tue, 29 Jun 2010, Michele Placci wrote:

...

Dear FreeSurfer Experts,

apart from the problem of my previous email I need to ask you more help,

can you write the link of a FreeSurfer Manual please? I'm not able to find it in the site: http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferWiki

My basic problem is:

I have two CD (for each patients) with a 3D MRI image and I have to assess and quantify brain atrophy from the first CD (time one) to the second CD (time two, away from the first few months) during the growth of the patients. If there were a precise list of instructions for this assess I'd be really happy.

Thanks a lot. Michele. _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer