Hi all, I've noticed that the tutorial's instructions for manual editing of the ventricles stops at about slice 92 (for Bert's data). Does this mean only the posterior portion of the lateral ventricles need to be filled, and that there is no need to continue to fill in the ventricles up to the anterior horns as well? Also, a couple more queries re: manual editing: - Sometimes I can see handles emanating from the surface that are not in the areas listed in the manual. Are there any guidelines re: what should be deleted as opposed to what should be filled? - Are there any guidelines for just how smooth the brain surface should be before moving on to create the final surface? Some of my surfaces appear quite smooth (ie., no obvious handles), although somewhat bumpy, esp. around the posterior-dorsal areas. - Am I correct in assuming that what is tissue is edited or not will affect surface generation and hence estimates of cortical thickness? In this case, is it advisable to carry out some kind of reliability analysis for morphmoteric studies?

Thanks for your help, Alex