Hi,

We have noticed differences in Talairach registration (and therefore ICV estimates) in some of our subjects from version 5.0 to version 5.1. Please see the attached document. There are 4 subjects, each row represents the same subject, same input images, same recon-all options (-all) between versions. The bottom of the second page has a table with the ICV values for these subjects across versions.

Have there been any changes to the Talairach registration step from 5.0 to 5.1 that would account for these differences?

Thanks, Jon