Hi Jessica,

if you only have little changes across longitudinal time points, CP edits can be transferred from the base (instead of the cross runs) into specific longitudinal runs by specifying the -uselongbasectrlvol when running the -long. See https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalEdits You should check if really all CP are meaningful in the longitudinal run.

The WM edits of the base should get the surfaces right. Long will be initialized with those better surfaces and the fine-tuning should not move them too far away, so it could be that edits in the long are not necessary. WM edits in the long have only limited influence. But they are important in the base.

Best, Martin

On 01/11/2016 03:25 PM, Collins, Jessica Ann wrote:

Dear FS Community,

I am currently using FreeSurfer 5.3 to conduct a longitudinal analysis of atrophy in Semantic Dementia. Because of the profound temporal pole atrophy in these patients, I have been making a lot of manual edits (mostly control points and wm edits) to the baseline scan, and these edits are often consistent across different time points for the same individual. I understand that with the longitudinal stream it is necessary to make edits to all cross-sectional scans, however I was wondering if there was any way to propagate manual edits made at one time point to future time points for the same subject? Any insight would be appreciated!

Best regards, Jessica

Jessica Collins, Ph.D. Postdoctoral Research Fellow Department of Neurology MGH-Harvard Medical School

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