Hi there, I am working on a project that involves pediatric data, ages 3-12. We are using Freesurfer to generate cortical surfaces. Information regarding the T1 acquisition is listed below. Is it appropriate to use the -3T and mprage flags for such data? Is there an alternative, pediatric atlas, that can be used for the Talariach and/or normalization steps that would be an improvement over the standard (or Schwartz) atlases?
Any input that you can provide would be greatly appreciated.
Cheers, Jason
Below please see some details on the MPRAGE that is being collected for my study.
GE 3T Signa® HDx MR scanner (GE Healthcare, Waukesha, WI) with an 8-channel head coil. During each session, 180 T1-weighted 1-mm3 isotropic volumetric inversion recovery fast spoiled gradient-recalled images (10 minute scan time), with cerebrospinal fluid (CSF) suppressed, were obtained to cover the whole brain with the following parameters: time of echo (TE) = 3.8 ms, time of repetition (TR) of acquisition = 8.6 ms, time of inversion (TI) = 831 ms, TR of inversion = 2332 ms, flip angle = 8°, field of view (FOV) = 25.6 cm × 25.6 cm, matrix size = 256 × 256, slice thickness = 1 mm, and receiver bandwidth = ± 20.8 kHz.
Hi Jason
it's hard to say a priori, particularly since this probably isn't even really an mp-rage (given that it's a GE scanner) and that you are using an 8 channel array. I guess I would say try it out and see.
As far as a pedi atlas, I'm not sure, perhaps Avi can comment?
Bruce
On Tue, 6 May 2014, Jason Tourville wrote:
Hi there, I am working on a project that involves pediatric data, ages 3-12. We are using Freesurfer to generate cortical surfaces. Information regarding the T1 acquisition is listed below. Is it appropriate to use the -3T and mprage flags for such data? Is there an alternative, pediatric atlas, that can be used for the Talariach and/or normalization steps that would be an improvement over the standard (or Schwartz) atlases?
Any input that you can provide would be greatly appreciated.
Cheers, Jason
Below please see some details on the MPRAGE that is being collected for my study.
GE 3T Signa® HDx MR scanner (GE Healthcare, Waukesha, WI) with an 8-channel head coil. During each session, 180 T1-weighted 1-mm3 isotropic volumetric inversion recovery fast spoiled gradient-recalled images (10 minute scan time), with cerebrospinal fluid (CSF) suppressed, were obtained to cover the whole brain with the following parameters: time of echo (TE) = 3.8 ms, time of repetition (TR) of acquisition = 8.6 ms, time of inversion (TI) = 831 ms, TR of inversion = 2332 ms, flip angle = 8°, field of view (FOV) = 25.6 cm × 25.6 cm, matrix size = 256 × 256, slice thickness = 1 mm, and receiver bandwidth = ± 20.8 kHz.
-- Jason A. Tourville, Ph.D. Research Assistant Professor Department of Speech, Language, and Hearing Sciences Boston University 677 Beacon St. Boston, MA 02215 Phone: (617)353-9484 Fax: (617)353-7755
freesurfer@nmr.mgh.harvard.edu