I used to have this about 20 years ago, but I stopped supporting it when it did not fit cleanly into the GLM ... The shortest route is probably to do two separate analyses with mri_glmfit, one for each group. This will output means and variances for each group. Then use fscalc to compute maps of the Welch's t.

On 3/11/19 1:28 PM, Hannah CK wrote:

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We are conducting t-test comparisons across groups in which there is a large discrepancy in group sizes. HOV is violated. I've searched for ways to run Welch's t-test in FreeSurfer (or a similar analysis that does not assume homogeneity of variance) but am not finding one.

Could anyone please advise on how to do this?

Thank you.

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