Hi Elisabeth,

don't mix versions. There is lots of stuff that can go wrong (files that don't exist in 4.5 cross that the longitudinal stream expects etc.). Since the longitudinal stream has been improved significantly since 4.5 (more reliability, several bug fixes etc) I'd recommend to re-run everything using 5.1.

Best, Martin

On Wed, 2012-07-04 at 10:12 +0000, Wenger, Elisabeth wrote:

Dear FreeSurfer experts,

we have processed a dataset crossectionally within version 4.5, and then ran the longitudinal stream with v5.1. we are interested in the hippocampus segmentations and now i'm wondering whether i should go back and run the whole analysis from scratch with the newest version. I understand that it might or even will give me slightly different results, but would it also be the assumption that the new results would be somewhat more correct, that is anatomically more accurate, because maybe for example the processing has been optimized for hippocampal segmentation or anything like that in the newer version? Or would they just be different, as they would also be different when running it on a different computer, Mac or PC, OSX version, etc?

Thank you very much for your help in advance!!

Best wishes, Elisabeth

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