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Hello, I have not tried it, but it would not surprise me to see incomplete library references when running the old freesurfer 5 binaries on the latest version of Mac OS, i.e., Mac OS 10.14 (Mojave) I would try to use the rev 6 release binaries for MacOS from, https://surfer.nmr.mgh.harvard.edu/fswiki/DownloadAndInstall I have built the latest development branch of freesurfer on Mac OS 10.14, but please be aware this has not been tested like the previous rev 6 release.  (I used the makefile.wiki to build it which you can download from https://surfer.nmr.mgh.harvard.edu/fswiki/CMake) - R. On Dec 23, 2018, at 10:00, Shachar Gal <gal.shachar@gmail.com> wrote:        External Email - Use Caution        Sorry, out of the office for the day. I'll get back to you about it tomorrowShacharOn Sun, Dec 23, 2018, 16:56 Glasser, Matthew <glasserm@wustl.edu> wrote:        External Email - Use Caution        Is that FreeSurfer 5.3?Matt.From: <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Shachar Gal <gal.shachar@gmail.com>Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>Date: Sunday, December 23, 2018 at 8:35 AMTo: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>Subject: Re: [Freesurfer] mpr2mni305 failed, during recon-all        External Email - Use Caution        this is my Freesurfer version - freesurfer-i386-apple-darwin10.8.0-stable5-20130513and I think the update to macOS Mojave was after successfully running the pipeline.you think this could be the issue? should I just upgrade my freesurfer?thanksOn Sun, 23 Dec 2018 at 16:28, Glasser, Matthew <glasserm@wustl.edu> wrote:        External Email - Use Caution        Which version of FreeSurfer is this and did you do some OS upgrade in between?Matt.From: <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Shachar Gal <gal.shachar@gmail.com>Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>Date: Sunday, December 23, 2018 at 8:24 AMTo: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>Subject: [Freesurfer] mpr2mni305 failed, during recon-all        External Email - Use Caution        hello,I'm running the hcp's FreeSurfer pipeline, and for some reason, after working successfully several times, on different subjects, im getting this error:***/Users/georgieboy/Research/Piano/test/222/222/mri\n mri_nu_correct.mni --n 1 --proto-iters 1000 --distance 50 --no-rescale --i orig.mgz --o orig_nu.mgz \n\n talairach_avi --i orig_nu.mgz --xfm transforms/talairach.auto.xfm \nERROR: mpr2mni305 failed, see transforms/talairach_avi.logDarwin medical613-6.tau.ac.il 18.2.0 Darwin Kernel Version 18.2.0: Fri Oct  5 19:41:49 PDT 2018; root:xnu-4903..221.2~2/RELEASE_X86_64 x86_64recon-all -s 222 exited with ERRORS at Sun Dec 23 15:50:23 IST 2018***the information in the talairach_avi.log is as follows:***dyld: Symbol not found: ___keymgr_global  Referenced from: /Applications/freesurfer/bin/gauss_4dfp  Expected in: /usr/lib/libSystem.B.dylib in /Applications/freesurfer/bin/gauss_4dfpAbortERROR: 'gauss_4dfp talsrcimg 1.1' failed! status=134ERROR: mpr2mni305 execution aborted***to be clear, this -  /usr/lib/libSystem.B.dylib exists exactly where is was expected...the input image, orig.mgz, looks fine and is in 1 mm res...so im having trouble getting to the bottom of the error.thanks in advance,Shachar The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail._______________________________________________Freesurfer mailing listFreesurfer@nmr.mgh.harvard..eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer%C2%A0The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail._______________________________________________Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer________________... mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer