Hi all,

I am using Freesurfer 5.0.0, before the outputs for cortical and subcortical GM and WM were made available in the final output files.

What is the best way to calculate total gray matter volume (cortical and subcortical)? Is it through mris_anatomical_stats or mri_segstats? Also, are there commands to calculate total cortical and total subcortical volumes of GM separately?

As for total white matter, is using the sum of the volumes of Left-Cerebral-White-Matter and Right-Cerebral-White-Matter considered acceptable practice? Or should I go to the command line and use mris_wm_volume?

Thanks in advance for the clarification, Dhinakaran.