Just ideas I had about how to set the contrast for ANOVA, but not sure if any of them is valid. Gabriel
Date: Fri, 18 Mar 2011 13:57:31 -0400 From: greve@nmr.mgh.harvard.edu To: gabriellbk@hotmail.com CC: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] 2x2x2 design
Gabriel, what are options 1 and 2 supposed to represent? doug
Gabriel Go.Es. wrote:
Dear Freesurfer experts, I'm wondering how to set a 2x2x2 anova
(diagnosis)x(gender)x(apoe)
g1MaleE4 g1MalenoE4 g1FemaleE4 g1FemalenoE4 g2MaleE4 g2MalenoE4 g2FemaleE4 g2FemalenoE4
option 1 [1 1 -1 -1 0 0 0 0] [1 1 0 0 -1 -1 0 0] [1 1 0 0 0 0 -1 -1] /2
option 2 [1 1 1 1 -1 -1 -1 -1] [1 1 -1 -1 1 1 -1 -1] [1 -1 1 -1 1 -1 1 -1] /4
And really have no idea about the interections between factors. Could you tell me for example how to evaluate the diagnosis x gender interaction effect and the interaction among the three factors (diagnosis x gender x apoe).
Bests regards, Gabriel
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-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
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Try this: [ 1 -1 -1 1 -1 1 1 -1]
This represents: ( (G1ME4-G1MnoE4) - (G1FE4-G1FnoE4) ) - ( (G2ME4-G2MnoE4) - (G2FE4-G2noE4) )
(G1ME4-G1MnoE4) = Diff between E4 and noE4 for Males in G1 (G1FE4-G1FnoE4) = Diff between E4 and noE4 for Females in G1 ( (G1ME4-G1MnoE4) - (G1FE4-G1FnoE4) ) - interaction between E4 and Gender for Group 1 ( (G2ME4-G2MnoE4) - (G2FE4-G2noE4) ) - interaction between E4 and Gender for Group 2
doug
(diagnosis)x(gender)x(apoe)
g1MaleE4 g1MalenoE4 g1FemaleE4 g1FemalenoE4 g2MaleE4 g2MalenoE4 g2FemaleE4 g2FemalenoE4
option 1 [1 1 -1 -1 0 0 0 0] [1 1 0 0 -1 -1 0 0] [1 1 0 0 0 0 -1 -1] /2
option 2 [1 1 1 1 -1 -1 -1 -1] [1 1 -1 -1 1 1 -1 -1] [1 -1 1 -1 1 -1 1 -1] /4
And really have no idea about the interections between factors. Could you tell me for example how to evaluate the diagnosis x gender interaction effect and the interaction among the three factors (diagnosis x gender x apoe).
Bests regards, Gabriel
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
The information in this e-mail is intended only for the person to
whom it is
addressed. If you believe this e-mail was sent to you in error and
the e-mail
contains patient information, please contact the Partners Compliance
HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to
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dispose of the e-mail.
freesurfer@nmr.mgh.harvard.edu
-
Douglas N Greve -
Gabriel Go.Es.