Hi, on 4 groups, 1 covariate (4GV1)
I run mri_glmfit using the following .mtx
C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0 C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0 C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0 C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0 C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0 C6) gr1-gr4_slope 0 0 0 0 1 0 -1 0 C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0 C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0 C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0 C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1 C11) gr3-gr4_intercept 0 0 1 -1 0 0 0 0 C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1 C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0 C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5 C15) group.effect.intercept 1 -1 0 0 0 0 0 0 1 0 -1 0 0 0 0 0 1 0 0 -1 0 0 0 0 C16) group.effect.slope 0 0 0 0 1 -1 0 0 0 0 0 0 1 0 -1 0 0 0 0 0 1 0 0 -1
Please: 1) Could you check whether the all .mtx are complete and corrected, in particular the gr1+gr2-vs-gr3+gr4.intercept and the gr1+gr2-vs-gr3+gr4.slope? 2) Could you explain the meaning of: gr1+gr2-vs-gr3+gr4.slope gr1+gr2-vs-gr3+gr4.intercept group.effect.slope group.effect.intercept 3) Which is the contrast identifying the effect of covariate on group differences?
Thanks
Best regards
Stefano
----Messaggio originale---- Da: "Douglas N Greve" greve@nmr.mgh.harvard.edu Data: 5-set-2017 22.59 A: freesurfer@nmr.mgh.harvard.edu Ogg: Re: [Freesurfer] R: Re: Map of covariance
you would need to create a contrast to look for the interaction. If you have four gruops and 1 covariate, then it would be
0 0 0 0 1 -1 0 0
0 0 0 0 1 0 -1 0
0 0 0 0 1 0 0 -1
On 09/05/2017 04:32 PM, stdp82@virgilio.it wrote:
Hi, e.g., by considering two or more groups, I would like to map the clusters reporting the covariance between the functional connectivity or cortical thickness (dependent variable) and age, tacking in account the group differences. Instead, I'm not interested to map the group differences, taking in account the nuisance factors. Thanks, Stefano
----Messaggio originale---- Da: "Douglas N Greve" greve@nmr.mgh.harvard.edu Data: 5-set-2017 18.12 A: freesurfer@nmr.mgh.harvard.edu Ogg: Re: [Freesurfer] Map of covariance
I don't understand what you are asking. can you elaborate?
On 08/30/2017 12:50 PM, stdp82@virgilio.it wrote:
Hi list, by applying a design e.g. 4GV1 in fsgd I could assess the dependence of group differences taking in account the effect of covariate. Anyway, where I should look if I want assess the the map showing the clusters in which the dependent variable is associated to covariate, tacking in account the group difference? Please could you suggest my the path? Thanks
Stefano
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
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-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
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On 10/01/2017 05:08 PM, stdp82@virgilio.it wrote:
Hi, on 4 groups, 1 covariate (4GV1)
I run mri_glmfit using the following .mtx
C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0 C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0 C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0 C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0 C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0 C6) gr1-gr4_slope 0 0 0 0 1 0 -1 0
should be
0 0 0 0 1 0 0 -1
C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0 C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0 C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0 C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1 C11) gr3-gr4_intercept 0 0 1 -1 0 0 0 0 C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1 C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0 C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5 C15) group.effect.intercept 1 -1 0 0 0 0 0 0 1 0 -1 0 0 0 0 0 1 0 0 -1 0 0 0 0 C16) group.effect.slope 0 0 0 0 1 -1 0 0 0 0 0 0 1 0 -1 0 0 0 0 0 1 0 0 -1
Please:
- Could you check whether the all .mtx are complete and corrected, in
particular the gr1+gr2-vs-gr3+gr4.intercept and the gr1+gr2-vs-gr3+gr4.slope?
they look correct, except for the one i noted
- Could you explain the meaning of:
gr1+gr2-vs-gr3+gr4.slope - does the average slope of grp1 and grp2 differ from that of grp3 and 4 gr1+gr2-vs-gr3+gr4.intercept - same group.effect.slope - interaction between group and covariate group.effect.intercept - is there an effect of group on the inercept 3) Which is the contrast identifying the effect of covariate on group differences?
not sure what you mean
Thanks
Best regards
Stefano
----Messaggio originale---- Da: "Douglas N Greve" greve@nmr.mgh.harvard.edu Data: 5-set-2017 22.59 A: freesurfer@nmr.mgh.harvard.edu Ogg: Re: [Freesurfer] R: Re: Map of covariance
you would need to create a contrast to look for the interaction. If you have four gruops and 1 covariate, then it would be
0 0 0 0 1 -1 0 0
0 0 0 0 1 0 -1 0
0 0 0 0 1 0 0 -1
On 09/05/2017 04:32 PM, stdp82@virgilio.it wrote:
Hi, e.g., by considering two or more groups, I would like to map the clusters reporting the covariance between the functional connectivity or cortical thickness (dependent variable) and age, tacking in account the group differences. Instead, I'm not interested to map the group differences, taking in account the nuisance factors. Thanks, Stefano
----Messaggio originale---- Da: "Douglas N Greve" greve@nmr.mgh.harvard.edu Data: 5-set-2017 18.12 A: freesurfer@nmr.mgh.harvard.edu Ogg: Re: [Freesurfer] Map of covariance
I don't understand what you are asking. can you elaborate?
On 08/30/2017 12:50 PM, stdp82@virgilio.it wrote:
Hi list, by applying a design e.g. 4GV1 in fsgd I could assess the dependence of group differences taking in account the effect of covariate. Anyway, where I should look if I want assess the the map showing the clusters in which the dependent variable is associated to covariate, tacking in account the group difference? Please could you suggest my the path? Thanks
Stefano
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it
is
addressed. If you believe this e-mail was sent to you in error and the e-
contains patient information, please contact the Partners Compliance
HelpLine
at
http://www.partners.org/complianceline . If the e-mail was sent to you in
error
but does not contain patient information, please contact the sender and
properly
dispose of the e-mail.
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu
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stdp82＠virgilio.it