Hi Nils

no, in general we don't recommend this. It adds unneeded variance (and maybe bias).

cheers Bruce

On Wed, 7 Mar 2018, Nils Opel wrote:

Hi Freesurfer Developers,

i am currently collecting structural imaging data from several large cohorts that have been processed using different freesurfer versions (5.3 and 6.0).

I would be interested on your experiences regarding compatibility between both versions for subcortical and cortical segmentations.

More specifically: would it be appropriate to include subcortical and cortical measures derived from both freesurfer versions (5.3 and 6.0) in the same analysis?

Thanks a lot in advance and best regards, Nils _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer