the reason, as i understand it, is that the analyze format does not store orientation information. this means there is no way to tell left from right, which can lead to problems in both atlas alignment, and during multimodal (fmri) registration.

n.

On Thu, 2010-08-26 at 13:32 -0500, Dr. Luis Guillermo Almeida Montes wrote:

Dear Nick:

Some colleagues asked me some doubts about pre-processing in FreeSurfer for MRI files. I remember you told me once that MRI files in analyze format would be inappropiate to pre-process in FreeSurfer suite. They work with this analyze format since their DICOM files can ´t be processed because their files are compressed.Can you give technicals details about the reasons about why analyze files cannot be used in FreeSurfer for pre-processing?

Thank you.

Best Regards. Dr. Luis G. Almeida