There are two things that are considered. One is the tesselation which smoothing is one. The other is the registration that is used. Using -target Something only specifies the smoothing target (if doing smoothing in mris_preproc). If you want to spec a registration target, you need to first run make_average_subject (which looks like you have done). Second, you need to run surfreg for each subject specifying your average subject with --t. This will create ?h.MyAverage.sphere.reg in each subject's surf folder. Then run mris_preproc with --surfre MyAverage.sphere.reg

doug

On 11/13/2014 05:06 AM, Roberta Santoro wrote:

Dear all,

I created an average subject from my dataset and I would like to use it to run a group analysis of thickness. I am using the command:

recon-all -s subjid -qcache -target MyAverage

When looking at the terminal, I noticed that the srcsurfreg and the trgsurfreg are both sphere.reg: shouldn’t one of the two be sphere.reg.MyAverage? Otherwise, how is the alignment achieved?

Thanks for your help.

Best,

Roberta

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