Hi Alex,

we have run plenty of studies with only one image/subjects. They require more time and manual intervention, and of course the study won't be as sensitive, but it is certainly doable. Don't try combining other contrast types though.

cheers, Bruce

On Mon, 18 Apr 2005, Fornito, Alexander wrote:

Hi, I am looking at running some thickness analyses on some MRI data we have already collected. I noticed that the manual states that "a minimum of two anatomical acquisitions is required for morphometric studies". Is it possible to run a valid thickness analysis in Freesurfer if I only have 1 T1 scan per person? Alternatively, a subset of our cohort have a T1 and T2, T1 and PD, or all three. Would it be possible to use a T1 and T2 instead of two T1s? Thanks for your help, Alex

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