On 12/7/19 5:42 PM, Alvarado,Luis R wrote:

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Hi all,

I have a couple of questions regarding fsaverage:

1. Is this file updated every time a new subject is process with recon-all?

No, fsaverage will not be changed.

1. If I obtain externally preprocessed datasets (e.g., from the 1000 Functional Connectomes Project) should I register those subjects to my local fsaverage?

Not sure what you mean. If you run the 1kFC anatomical data through recon-all, they will automatically be registered

1. 1. Ultimately, I would like to conduct an ROI analysis of the differences between normative data from a large online biobank and locally imaged patient population. The workflow for such analysis recommended on (https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI) suggests to draw ROI labels directly on fsaverage (*/_a template to which all subjects run with FreeSurfer have been registered to_/*) and then use the mri_label2label command to map the label to individual subjects. Would this work for both locally and externally preprocessed groups?

Yes

1.

Thank you,

Luis R. Alvarado

Ph.D. Candidate

Department of Anatomical Sciences and Neurobiology

University of Louisville School of Medicine

Kentucky Spinal Cord Injury Research Center

220 Abraham Flexner Way, Suite 1500

Louisville, KY 40202

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