Dear all,
I am posting the questions I made to Bruce without going through the list
along with his reply.
**I would still like to be sure about question 1)***, as it is central to my
conclusions. If anyone has any other ideas, please let me know.
>There are still a couple of questions in my mind I would really like to
> understand concerning this TIV estimation though:
> 1) I first run FS without any visual inspection (-autorecon1 and 2) to get
> the TIV estimate in the aseg.stats file. I then compared those values to
the
> ones obtained *after* adjusting the affine transf (in some cases using the
> brain.mgz file, others manually) and the values changed. But is this the
> correct procedure to adjust the TIV output, or am I looking at an
artifact?
> 2) Is it possible for me to build my own template for TIV estimation
> purposes? If yes, which file should be replaced?
> Thank you again for your help (btw, is there any chance I can obtain the
> eTIV value without running -autorecon1 and 2 all the way?)
Reply:
>(1) We have very little experience with the eTIV, but I guess
>the answer is yes, that would be the way to do it, and (2) the only way to
>build your own atlas would be to use the aseg.mgz from a bunch of subjects
>and mris_ca_train.
Although 2) is possible in a practical way (ie, I can build my own atlas), I
don't believe it would be valid for TIV estimation with FS, due to the
bootstrap method you used to calculate the "scale factor". Am I right?
Finally, could someone please explain me the point of trying to adjust the
talairach output by using the T1.mgz and brain.mgz files? I know this works,
but I don't understand why, especially with the brain.mgz: the reference
atlas has skull... shouldn't using a skull stripped scan confound the
process?
Thank you all.
Hope to hear from you soon.
Joao