Freesurfer November 2008

freesurfer@nmr.mgh.harvard.edu

70 participants
98 discussions

for cortical thickness
by Zhang, Xiaochu (NIH/NIDA) [F] 14 Nov '08

14 Nov '08

Hi FreeSurfer Expert, Can I transfer the thickness data into other form, for example, Nifti, AFNI or SPM? Thanks a lot! Xiaochu Zhang PhD Visiting Research Fellow Neuroimaging Research Branch National Institute on Drug Abuse - IRP Biomedical Research Center 251 Bayview Blvd. Suite 200 (NIDA) Baltimore MD 21224 Tel: 443-740-2619

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Re: Atlases
by sameer kumar 14 Nov '08

14 Nov '08

Hi all, I am trying to find the atlases in the freesurfer directory. I could not find the specific atlases sub directory. Is there a sub directory that contains all the atlases like the MNI, JHU, etc? Regards, Sameer Kumar Gottipati

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volumes of a 2 mm scan and a global thickness measure.
by asaf achiron 14 Nov '08

14 Nov '08

dear group, we acquired a scan of 2 mm. I know we cannot use FREESURFER to measure cortical thickness. however, can we use it to measure all the volumes like the Thalamus, Hippocampus, Amygdala etc.. in addition, in other scan of 1x1x1 we would like to know the whole cortex thickness and the thickness in each lobe, because in the aparc.stats we get for specific region. thank you Asaf

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tksurfer ftimepoint variable
by Yigal Agam 14 Nov '08

14 Nov '08

Hi, I'm trying to use a TCL script that runs through every time point in a surface. I'm using the following commands: set gaLinkedVars(ftimepoint) 0 (or 1, 2, etc) SendLinkedVarGroup overlay But tksurfer is always showing point 0 (doesn't advance in time). Similar TCL commands for fthresh and fslope work fine. Any ideas?

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Antw: Re: [Freesurfer] absolute curvature values for vertex-wise comparison
by Carl Schultz 14 Nov '08

14 Nov '08

Hi Bruce, thank you very much. That' s what I looked for. Best regards, Christoph >>> Bruce Fischl <fischl(a)nmr.mgh.harvard.edu> 13.11.08 14.43 Uhr >>> Hi Carl, you could read them into matlab, take the absolute value, and write them back out again if you want, then run a glm on that. load_mgh and save_mgh are the matlab i/o routines. cheers, Bruce On Thu, 13 Nov 2008, Carl Schultz wrote: > Dear all, > > for a vertex-wise comparison of the mean curvature is there a > possibility to change the signed curvature values from the preprocessed > curv.mgh to unsigned (absolute) values for the glm? > > Thanks in advance, > > Christoph > ____________________ > Universitätsklinikum Jena > Körperschaft des öffentlichen Rechts und Teilkörperschaft der > Friedrich-Schiller-Universität Jena > Bachstraße 18, 07743 Jena > Verwaltungsratsvorsitzender: Prof. Dr. Walter Bauer-Wabnegg; > Medizinischer Vorstand: Prof. Dr. Klaus Höffken; > Wissenschaftlicher Vorstand: Prof. Dr. Klaus Benndorf; Kaufmännischer > Vorstand und Sprecher des Klinikumsvorstandes Rudolf Kruse > Bankverbindung: Sparkasse Jena; BLZ: 830 530 30; Kto.: 221; > Gerichtsstand Jena > Steuernummer: 161/144/02978; USt.-IdNr. : DE 150545777 > > _______________________________________________ > Freesurfer mailing list > Freesurfer(a)nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > ____________________ Universitätsklinikum Jena Körperschaft des öffentlichen Rechts und Teilkörperschaft der Friedrich-Schiller-Universität Jena Bachstraße 18, 07743 Jena Verwaltungsratsvorsitzender: Prof. Dr. Walter Bauer-Wabnegg; Medizinischer Vorstand: Prof. Dr. Klaus Höffken; Wissenschaftlicher Vorstand: Prof. Dr. Klaus Benndorf; Kaufmännischer Vorstand und Sprecher des Klinikumsvorstandes Rudolf Kruse Bankverbindung: Sparkasse Jena; BLZ: 830 530 30; Kto.: 221; Gerichtsstand Jena Steuernummer: 161/144/02978; USt.-IdNr. : DE 150545777

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Antw: Re: [Freesurfer] absolute curvature values for vertex-wise comparison
by Carl Schultz 14 Nov '08

14 Nov '08

Dear Rudolph, thank you very much for your reply. I used the load_mgh command in matlab for the preprocessed curv.mgh to create the absolute_curvature _values.mgh, which was successful. Best regards, Christoph >>> Rudolph Pienaar <rudolph(a)nmr.mgh.harvard.edu> 13.11.08 22.44 Uhr >>> On Thursday 13 November 2008 08:23:08 Carl Schultz wrote: > Dear all, > > for a vertex-wise comparison of the mean curvature is there a > possibility to change the signed curvature values from the preprocessed > curv.mgh to unsigned (absolute) values for the glm? > The newest (i.e. dev) version of 'mris_calc' will do this: $>mris_calc rh.curv abs This will run an 'abs' (absolute value) function on each element in 'rh.curv'. Output is saved by default to 'out.crv'. You can specify a more meaningful output with '--output <someFile>', so $>mris_calc --output rh.curv.abs rh.curv abs Since this is only in the 'dev' tree, let me know if you'd like a binary. -=R -- Rudolph Pienaar, M.Eng, D.Eng / email: rudolph(a)nmr.mgh.harvard.edu MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging 149 (2301) 13th Street, Charlestown, MA 02129 USA _______________________________________________ Freesurfer mailing list Freesurfer(a)nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer ____________________ Universitätsklinikum Jena Körperschaft des öffentlichen Rechts und Teilkörperschaft der Friedrich-Schiller-Universität Jena Bachstraße 18, 07743 Jena Verwaltungsratsvorsitzender: Prof. Dr. Walter Bauer-Wabnegg; Medizinischer Vorstand: Prof. Dr. Klaus Höffken; Wissenschaftlicher Vorstand: Prof. Dr. Klaus Benndorf; Kaufmännischer Vorstand und Sprecher des Klinikumsvorstandes Rudolf Kruse Bankverbindung: Sparkasse Jena; BLZ: 830 530 30; Kto.: 221; Gerichtsstand Jena Steuernummer: 161/144/02978; USt.-IdNr. : DE 150545777

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absolute curvature values for vertex-wise comparison
by Carl Schultz 13 Nov '08

13 Nov '08

Dear all, for a vertex-wise comparison of the mean curvature is there a possibility to change the signed curvature values from the preprocessed curv.mgh to unsigned (absolute) values for the glm? Thanks in advance, Christoph ____________________ Universitätsklinikum Jena Körperschaft des öffentlichen Rechts und Teilkörperschaft der Friedrich-Schiller-Universität Jena Bachstraße 18, 07743 Jena Verwaltungsratsvorsitzender: Prof. Dr. Walter Bauer-Wabnegg; Medizinischer Vorstand: Prof. Dr. Klaus Höffken; Wissenschaftlicher Vorstand: Prof. Dr. Klaus Benndorf; Kaufmännischer Vorstand und Sprecher des Klinikumsvorstandes Rudolf Kruse Bankverbindung: Sparkasse Jena; BLZ: 830 530 30; Kto.: 221; Gerichtsstand Jena Steuernummer: 161/144/02978; USt.-IdNr. : DE 150545777

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A problem on groupanalysis
by Zhangyuanchao 13 Nov '08

13 Nov '08

Dear Mr or Ms, I have read the FreeSurfer Tutorial: Group Analysis, but there are still something I do not quite understand. I want to make comparison of lgi between two groups, namely, normal control group and patient group. I want to regress out gender and age.For example,if I have 4 subjects: nc1 male age=30,nc2 female age=31,patient1 male age=32, patient2 female age=30, how should I create the FSGD file?How should I design the constrast vector? What kind of test does Freesurfer use,F-test or t-test to detect difference region of thickness or lgi on the surface? What should I do if I want to use t-test to detect the difference between two groups? How should I set the option of the command mri_glmfit --sim nulltype nsim thresh csdbasename if I want to set the p-value threshold 0.05? Sorry for the trouble! Thank you very much! Yuanchao Zhang --------------------------------- 雅虎邮箱，您的终生邮箱！

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Qdec problem?
by Martin Kavec 13 Nov '08

13 Nov '08

Hi, I am trying to run a group analysis on cortical thickness between patients and controls. In the qdec.dat I set a MMSE for all the controls 0.0. Now, whenever I try to covariate thickness against age and MMSE, the qdec complains that there is no spectrum in MMSE values. I tried to set MMSE for one of controls to 0.1 and the analysis goes fine. After thinking for a while, I started to wonder whether I shouldn't calculate thickness difference first, but I am not finding the receipt on the web anymore. Thanks in advance, Martin

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mri_convert --conform spatial changes
by Arthur Mikhno 13 Nov '08

13 Nov '08

Hi, I am trying to convert the ribbon (amongst other mgz files) from a freesurfer run to the native space ANALYZE file I initially imported into freesurfer. I need to do this to create a cortical ribbon mask as a pre-processing step for normalization (with another package). However, every mgz file in the mri/ folder, after conversion, has a slightly different spatial distribution after conversion. Although, when I convert 001.mgz and rawavg.mgz the resultant image matches the image I imported exactly. By spatial distribution I mean, minor cortical fold shifts (up down, left right) and individual minor rotations in the cortical folds, some minor internal translations. I think I tracked the problem down to the conform step, when rawavg.mgz gets conformed (mri_convert --conform) to 1x1x1mm and saved as orig.mgz. I need to ensure a spatially correct cortical ribbon in the native space data. Is there any way to un-conform ? or some way to say, convert orig.mgz BACK to rawavg.mgz? For reference, this is the command I am using to convert .mgz to ANALYZE (.hdr, .img): mri_convert --out_orientation LSP -rl native_mri.img orig.mgz converted_native_mri.img I would really appreciate any help as this is my LAST roadblock! Thanks in advance, -Arthur

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Freesurfer November 2008