Hi all,
My team has recently completed a few hundred FreeSurfer runs on young (2-4
year old) children. For the past month or so, we have been using various
editing techniques in order to fix different problems with the white matter
volumes (these were to be expected considering the ages of our subjects).
Since our goal is to get accurate measurements of cortical thickness, this
is a crucial step.
A few of the images simply stop including the white matter at a certain
point, always always toward the posterior/occipital region of the brain. We
devised an approach to solving this problem that involves converting formats
and orientations, loading the brainmask and white matter volume into a
manual brain segmentation editing tool, and using a 'snake tool' that fills
in the white matter that was not captured by FreeSurfer. We have ensured
that the label we used to fill this in is the same as the label used for
manual editing within tkmedit. HOWEVER, after rerunning FreeSurfer with
this edited volume (using -autorecon2-wm), the surfaces do not seem to have
changed at all.
Am I missing something here? I thought that if white matter edits were made
that filled in gaps in the original wm.mgz volume, FreeSurfer would adjust
the the surfaces accordingly.
I've attached two photos to give you an idea of what I'm experiencing.
Thanks for any advice on this predicament.
Ryan