Hello all,
I would like to know whether the T1 parameters such as TR, TE, TI, and
flip angle can systematically influence mean curvature values obtained by
recon-all -all.
I have processed 2 data sets with the following T1 parameters, and am
noticing that the mean curvature values systematically bigger in the
former compared to the latter data set in 78% of the brain regions
segmented in the default (Desikan) atlas.
data set 1:
TR=12.24, TE=3.56, TI=530.00, flip angle=23.00
Original Data has (1, 1, 1) mm size and (240, 256, 176) voxels
data set 2:
TR=20.66, TE=8.42, TI=640.00, flip angle=25.00
Original Data has (1, 1, 1) mm size and (224, 256, 176) voxels
More generally, I would like to confirm that it's not recommended to
combine data based on different scanning parameters in one study, due to
possible systematic differences in the segmentation output related to
scanning parameters.
thanks in advance and all the best,
Narly.