Hi freesurfer masters,
Quick question on the way freesurfer calculates the dice coefficient. I
am interested in getting an INTERsubject dice coefficient as a measure
of similarity between 2 subjects. My question is, do I need to do an
INTERsubject registration step before calculating the dice in
freesurfer? In other words, does freesurfer do any kind of INTERsubject
registration at the level of the aseg.mgz file? If it does not, when it
calculates an intersubject dice coefficient, a low result could be due
simply to poor alignment between scans and not poor anatomical
correlation. If anyone has details please let me know.
Cheers,
Jared