Dear List,
in an attempt to divide grey matter segments into an outer and inner
layer, I am currently using the vertex coordinates for pial surface (in
Matlab>> read_surf('lh.pial') ) and vertex coordinates for white matter
surface (MATLAB>>read_surf('lh.white') ). Perhaps naively, I assume,
that the order of the two coordinate matrices is identical and calculate
the wanted coordinates of a point on a line (say half way) in between
the corresponding pial and white matter vertices.
What puzzles me is that the distances between corresponding (?) white
matter and pial surface vertices are not equal to the cortical thickness
values given by >>read_curv('lh.thickness')
(GM-WM distances up to 9.3 mm are found, whereas cortical thickness
values vary between -0.24 and 5 mm in the data set I am working on)
--> To determine a layer, separating outer from inner half of the
cortex, would it be a more valid to
A: determine vertex normals of pial surface and travel along them by a
distance 1/2 the cortical thickness? (Q: which thickness value belongs
to which vertex? where do the negative thickness values come from?)
or
B: determine points half way in between vertex coordinates of
corresponding pial and WM vertices? (Q: how can I assure their
correspondence?)
Is anyone working on / has solved a related problem? Any hint would be
greatly appreciated!
Cheers,
Kai
--
Dr. Kai Lutz
Neuropsychology
Institute for Psychology
University of Zurich
Binzmühlestrasse 14 /Box 25
CH-8050 Zürich
Switzerland
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