Dear Freesurfer Team,
I am an image processing novice and am trying to register resting-state
data to an anatomical scan using bbregister. The T1s have been run through
Freesurfer's reconall pipeline, and the EPIs have undergone the following
preprocessing steps:
- slice time correctoin
- deobliquing
- drop first few images
- motion correction / volume registration
- despike
- temporal filter
- smoothing
(I tried registering EPIs that had been aligned to MNI space to the
anatomicals, with similar outcomes.)
Ultimately, I plan to use Freesurfer-generated ROIs (those from Yeo et al.,
2011), based on the anatomical scan, to run graph theory analyses on the
resting-state data.
However, when I use bbregister, the files are grossly misaligned. Below is
an image of the EPI file on top of the white matter surface (in green). You
can see that the EPI file looks very large.
Has anyone encountered this problem / does anyone have any suggestions as
to what I might be doing wrong? Any help would be greatly appreciated.
Thank you in advance for your time.