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Hi,
I am still struggling to examine differences in thickness using the command line stream for my two groups after controlling for age and sex. I get the following error when running the command line:
ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08
--------------------------------
Possible problem with experimental design:
Check for duplicate entries and/or lack of range of
continuous variables within a class.
If you seek help with this problem, make sure to send:
1. Your command line:
mri_glmfit.bin --y CAA_CTRL_RH.thickness.10.mgh --fsgd
CAA_CTRL_RH_Age_Sex.fsgd --C Contrasts/CAA-CTRL_Age_Sex.mtx --surf fsaverage rh
--cortex --glmdir CAA_CTRL_RH_Age_Sex_Unix.glmdir
2. The FSGD file (if using one)
3. And the design matrix above
Attempting to diagnose further
SumSq: Min=0.000000 (col 5), Max=611.699463 (col 4)
The scale is much different between columns 5 and 4, you may want to
normalize by subtracting the mean and dividing by the standard deviation.
Column 5, all values are 0
Column 6, all values are 0
Columns 5 and 6 are the same
My design matrix is:
1 -1 0 0 0 0 (Examining difference in thickness after controlling for effects
of age and sex)
I’ve also attached the FSGD file that I’ve been using. Please let me know if there is something wrong with the file (although I have used a similar file without the covariates and did not have any issues).
Thanks!
Arsenije
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Arsenije Subotic | MSc Student
Department of Clinical Neurosciences
Hotchkiss Brain Institute, University of Calgary | T2N 4N1, Canada
Tel: (403) 918-6970
arsenije.subotic1(a)ucalgary.ca<mailto:arsenije.subotic1@ucalgary.ca>