Freesurfer February 2021

freesurfer@nmr.mgh.harvard.edu

98 participants
118 discussions

Question about statistical data for cerebellar segmentation ?
by Viktor-Jan De Deken 23 Feb '21

23 Feb '21

External Email - Use Caution Hi Freesurfer I would like to perform statistical analesys on cerebellar segmentation data. For my purposes, The atlases that come with Freesurfer don't give enough parcellation of the cerebellum. I tried looking online and found this email conversation: https://secure-web.cisco.com/1229EcuHvdmZnZf2i3VnPduj5r7wBNepLb6mPJVJg1F2on… I applied this and it worked visually but I want statistical data like in the aseg.stats or aparc.stats files. Can you help me? Kind regards Viktor-Jan

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recon-all error: No such file or directory
by Eduardo Bergonzoni Junqueira 23 Feb '21

23 Feb '21

External Email - Use Caution Hello FreeSurfer Developers, I'm attempting to preprocesss a t1.nii.gz image in freesurfer with recon-all. I'm following the tutorial for linux in https://secure-web.cisco.com/1LNJqjy9_CcjRF6N2vjvepp4rKUty6HrwT4CmaUGa6hhi_…. (base) eduardo@eduardo-X555UB:~/Área de Trabalho/Grant_Tractography$ export FREESURFER_HOME=/usr/local/freesurfer (base) eduardo@eduardo-X555UB:~/Área de Trabalho/Grant_Tractography$ . $FREESURFER_HOME/SetUpFreeSurfer.sh -------- freesurfer-linux-centos6_x86_64-7.1.1-20200723-8b40551 -------- Setting up environment for FreeSurfer/FS-FAST (and FSL) FREESURFER_HOME /usr/local/freesurfer FSFAST_HOME /usr/local/freesurfer/fsfast FSF_OUTPUT_FORMAT nii.gz SUBJECTS_DIR /usr/local/freesurfer/subjects MNI_DIR /usr/local/freesurfer/mni FSL_DIR /home/eduardo/fsl I'm getting the following error when I run the command: (base) eduardo@eduardo-X555UB:~/Área de Trabalho/Grant_Tractography$ recon-all -s Grant_sub -i t1.nii.gz -all ERROR: /home/eduardo/\301rea de Trabalho/Grant_Tractography: No such file or directory. This error is strange for me. I don't know why it is showing "\301rea de Trabalho/" if the correct name of the directory is "Área de Trabalho". The t1.nii.gz is in the path directory I'm using in the terminal. Please, can anybody help how to fix this bug? I've looked for similar bug reports. Probably it is something simple, but I couln't found how to solve the problem. 1) FreeSurfer version: freesurfer-linux-centos6_x86_64-7.1.1-20200723-8b40551 2) Platform: Ubuntu 20.04.1 3) uname -a: Linux eduardo-X555UB 5.8.0-43-generic #49~20.04.1-Ubuntu SMP Fri Feb 5 09:57:56 UTC 2021 x86_64 x86_64 x86_64 GNU/Linux Best regards

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Brain normalisation to intracranial volume
by Carolina Rimkus 23 Feb '21

23 Feb '21

External Email - Use Caution I would like to know which are the best ways to normalize the VOI's to intracranial volume. Also, what is the variable BrainSegVol-to-eTIV in aseg? Is it a scaling factor? Does freesurfer segmentation provide a scaling factor? Best regards, Carolina -- Carolina M Rimkus, MD, PhD Neuroradiologist Department of Radiology, Faculty of Medicine, University of São Paulo-SP, Brazil email: carolina.rimkus(a)usp.br carolina.rimkus(a)gmail.com

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Drawing labels on flat patch.
by Devavrat Vartak 22 Feb '21

22 Feb '21

External Email - Use Caution Hello freesurfer experts, Freeview v3.0 FS 7.1.1 I am able to draw labels on the 3D surface and display it on a flat patch, but when I try to draw directly on the flat patch it keeps drawing in the 3D-space. Is it possible to draw labels on the flat patch directly ? Thank you. Cheers, Dev

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Application for Chinese Postdoctoral Scholarship on Dynamic Brain Connectivity
by Joana Braga Pereira 22 Feb '21

22 Feb '21

External Email - Use Caution Dear all, If you have earned a PhD degree in China in the last 3 years and would like to do a Postdoc at Karolinska Institute in Sweden, please see the project below: *Dynamic Changes in Functional Brain Connectivity over the course of Alzheimer’s Disease* The aim of this project is to apply new methods that analyse brain connectivity as a highly dynamic process across different stages of AD. This will be performed by combining resting state functional magnetic resonance imaging with graph theory methods in different cohorts of patients and healthy controls. Once the dynamic brain network changes have been identified, their relationship with CSF biomarkers and cognitive function will be assessed. In addition, it will also be possible to apply machine-learning algorithms in this project as well as combine the data with anatomical brain connectivity measures derived from diffusion tensor imaging. The ideal candidate should have the following qualities: - A PhD in neuroimaging, computational science, engineering, physics, medicine, statistics, neuropsychology or a related field; - Experience in statistical techniques, programming, or scripting; - Experience with functional magnetic resonance imaging, diffusion tensor imaging, positron emission tomography or other neuroimaging techniques; - Clinical or research experience with aging and/or neurodegenerative disorders; - Good writing and communication skills in English; - Good record of scientific publications. If you are interested in applying for a scholarship, please send an email with your CV to *joana.pereira(a)ki.se <joana.pereira(a)ki.se> *as soon as possible. Best wishes, Joana

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overlap/intersection of labels?
by Dr. Cornelius Kronlage 22 Feb '21

22 Feb '21

External Email - Use Caution Dear freesurfers, is there an elegant way of computing the intersection or overlap of different labels or - which would be even more useful for my application - annotations? I only managed to find labels_intersect (which appears to be from https://secure-web.cisco.com/12D3ntbm8RDBV366hh41UjEkFWk2mrjQHSMiY8WEom0naU… ) which is awfully slow. In case this is of use for anyone else, I attached a modified version using 'join' that runs much faster, only has some compatibility issues with Mac. >time labels_intersect precentral.label frontal.label out1.label > /dev/null real 1m41.862s user 0m31.052s sys 0m30.757s >time bash bash_labels_intersect.sh precentral.label frontal.label out2.label real 0m0.193s user 0m0.118s sys 0m0.015s >diff -w out1.label out2.label > Thank you and best wishes Cornelius -- Cornelius Kronlage Assistenzarzt Klinik für Neurologie | Neurologie mit Schwerpunkt Epileptologie Universitätsklinikum Tübingen Hoppe-Seyler-Str. 3 | 72076 Tübingen

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Hippocampal subfield segmentation by T2 scan
by Wei Shao 19 Feb '21

19 Feb '21

External Email - Use Caution Hi, dear Freesurfer team I used sagittal T1(MPRAGE-sag_T1w.nii.gz) to recon-all and did the hippo-subfield segmentation on T1, but when I tried to use the additional scan by segmentHA_T2.sh : segmentHA_T2.sh sub-AVP14352 /home/weishao/sub-AVP14352/Ses-01/anat/sub-AVP14352_ses-01_cor_run-01_T2w.nii.gz sub-AVP14352_T2 0 Here is the feedback Error using kvlGEMSMatlab std::bad_alloc Error in kvlReadCroppedImage (line 11) Error in segmentSubjectT2_autoEstimateAlveusML (line 930) @#@FSTIME 2021:02:19:13:38:45 run_segmentSubjectT2_autoEstimateAlveusML.sh N 18 e 385.18 S 24.62 U 646.85 P 174% M 1033292 F 130 R 2612883 W 0 c 193519 w 290275 I 2443704 O 429952 L 3.35 3.58 5.40 @#@FSLOADPOST 2021:02:19:13:45:10 run_segmentSubjectT2_autoEstimateAlveusML.sh N 18 5.71 5.26 5.58 Linux gra-login1 3.10.0-1127.8.2.el7.x86_64 #1 SMP Tue May 12 16:57:42 UTC 2020 x86_64 GNU/Linux T2 hippocampal subfields exited with ERRORS at Fri Feb 19 13:45:11 EST 2021 Could you tell me what I should do to fix this? Thanks Best, Wei

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multiple comparisons correction
by Agurne Sampedro Calvete 19 Feb '21

19 Feb '21

External Email - Use Caution Dear Freesurfer experts, I am doing a longitudinal repeated measures ANOVA 2x2, with two groups (experimental vs control) and two time points (pre and post treatment). I have followed the group analysis tutorial ( https://secure-web.cisco.com/1pRD_UxgiIfPoYGdD-txQXbrB2PxuCy8sHKMjDgu-jv8mY… ), where it is suggested to do a Z Monte Carlo simulation with the following command: mri_glmfit-sim \ --glmdir lh.gender_age.glmdir \ --cache 4 neg \ --cwp 0.05\ --2spaces However, I have two questions regarding this issue: 1) I would like to know whether is it correct to use for example --cache 3 or 2 instead of 4. Is it recommended? 2) Is it better to use, instead of the above Z Monte Carlo simulation command, a permutation with the following command?: mri_glmfit-sim \ --glmdir lh.gender_age.glmdir \ --perm 1000 4.0 abs \ --cwp 0.05\ --2spaces \ --bg 1 Is it appropriate to use any of both? I do not know which is more recommended or whether both are adequate so I can simply choose, for example, the first one. Thank you very much in advance. Kind regards, Agurne Neuropsychology of Severe Medical Conditions Research Team Dpt of Methods and Experimental Psychology Faculty of Psychology and Education University of Deusto neurolab.deusto.es Avda. de las Universidades 24, 48007, Bilbao (Spain) Phone: +34 944139000 (ext. 3015)

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3 groups comparison question (mri_glmfit)
by 김용갑 19 Feb '21

19 Feb '21

External Email - Use Caution Deer Freesurfer Experts, We are trying to perform 3 group comaprison analysis in Freesurfer (mri_glmfit). Our fixed factors are "group (Case1, Case2, Healthy)" and our dependent variables are "thickness variables".We want to control "CPZ" continuous variable but CPZs of healthy group are all zero.So, it makes following errors in Freesurfer 1. ill-conditioned problem, Freesurfer design matrix maybe be linearly-dependent 2. Badly scaled problem, CPZ variables are higly different between groups (Case1, Case2 have big CPZ variables, but Healthy have all zero) To solve this problem, we are going to make own design matrix using only two indicator varibles for three groups.(Freesurfer's design matrix seems to use three indicators, which may make error in this analysis)And we are going to change the contrast to suit my design matrix with two indicators. Is it possible to use two indicator design matrix in Freesurfer to perform 3 group comparison analysis(mri_glmfit)?mri_glmfit help page said that the design matrix can be specified in matlab4 format, can't in excel?, Shoud it be version 4 in the matlab?Finally, to solve badly scaled problem, can i use z-score calculated on all group samples? Best regards, Yonggab Kim

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convert BA probability labels to volume
by julienbesle 19 Feb '21

19 Feb '21

External Email - Use Caution Hello, I'm trying to convert label files containing probability values for Brodmann areas (e.g. rh.BA1_exvivo.label) to volume files using mri_label2vol. I'd like to keep the probability value that's in the 5th column of the label file into the volume, but mri_label2vol sets all voxels in the label to 1 (i.e. creates a mask). Is there a way to do this? Thanks Julien -- ------------------------------------------------------ Julien Besle Assistant Professor Department of Psychology Faculty of Arts and Sciences American University of Beirut Riad El-Solh / Beirut 1107 2020 Lebanon Jesup Hall, Room 103E Tel: +961 1 350 000 ext. 4927 -----------------------------------------------------

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Freesurfer February 2021