Dear Freesurfer experts:
we would appreciate if anyone could advise on the sign
choice of Monte Carlo simulation, a
question we posted 2 days ago.
In examining QDEC results of a contrast of interest, we noticed
the results are mainly in cold color (blue), with only two small clusters in
warm color (red). When I proceeded with Monte Carlo simulation, if I chose the
abs as the sign option in simulation, then no clusters survived. In contrast,
some clusters would remain, if I chose the neg sign. Because the uncorrected
results were mainly in cold color, it seems reasonable to me to use negative
only in the simulation. But I am wondering how the option of abs/neg/pos leads to the disparities and will
you please elaborate how the simulation works based on abs/neg/pos. Can I state that my results survived the
cluster-level correction if I chose the neg sign in simulation?
Thank you very much.
Karl