Dear freesurfer experts:
We are using freesurfer to preform a cortical thickness analysis
between patients and controls. We plan to use the mean_thickness and
subject age as covariates. It's fine to analysis as group x age or
group x mean_thickness, respectively. But when we set design as group
x age x mean_thickness, an error report appeared in the terminal:
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Matrix condition is 11355.6
ERROR: matrix is ill-conditioned or bad scaled, condno = 11355.6
Possible problem with experimental design:
Check for duplicate entries and /or lack of range of continuous
variables within a class.
(continuous with values in Xg.dat)
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Does the problem course by the different "range" from age value
(between 18-28) and mean_thickness (between 2-4) with in the same
subject? if so, how can we solve it? Does proportional scaling on age
or mean_thickness help?
Any comments are welcome and very appreciate.
--
Best regards
--
杜政昊
Cheng-Hao Tu, PhD Student
Laboratory of Integrated Brain Research
Department of Medical Research and Education
Taipei Veterans General Hospital
No.201, Sect.2, Shih-Pai Rd.
Taipei
Taiwan
Email: lordowen(a)ms10.hinet.net or lordowentu(a)gmail.com
Tel: +886-2-28712121 ext 3474
Fax: +886-2-28745182