answers below. also, please remember to post to the list
On 8/21/2020 6:52 PM, Rizvi, Batool wrote:
>
> Â Â Â Â Â Â Â Â External Email - Use Caution
>
> Thank you Dr. Greve! This is very helpful! Just to confirm, similar to
> taking the effect of age, if I wanted to get the beta of Parietal WMH
> (my main continuous IV), I would just average betas 5-8?
>
> I forgot to add this in my previous email, but I’m also trying to
> extract p-values of all the variables involved, and wasn’t sure how
> to. I tried running a couple different commands.
>
> When I ran this below command, I got a file with 1 column of 8 numbers:
>
> mri_segstats --i contrasts.sig.mgh --annot fsaverage lh
> lh-Avg-long.thickness-spc-Parietal_WMH-Cor/mc-z.abs.th20.sig.ocn.annot
> --excludeid 0 --avgwf avgwfsig.dat
>
where did contrasts.sig.mgh come from? Was this created by QDEC?
>
> But when I tried the below command, I got a file with 1 number.
>
> mri_segstats --i lh-Avg-long.thickness-spc-Parietal_WMH-Cor/sig.mgh
> --annot fsaverage lh
> lh-Avg-long.thickness-spc-Parietal_WMH-Cor/mc-z.abs.th20.sig.ocn.annot
> --excludeid 0 --avgwf avgwfsig2.dat
>
> From the 1^st way (using contrasts.sig.mgh):
>
> Â Â -0.27711
>
> Â Â Â -2.51072
>
> Â Â Â Â 0.42697
>
> Â Â Â Â 0.62922
>
> Â Â Â -0.85069
>
> Â Â Â Â 0.52623
>
> Â Â Â Â 1.00393
>
> Â Â Â -0.42921
>
> From the 2^nd way (using sig.mgh)
>
> Â -2.51072
>
> I’m pasting my fsgd format once more:
>
> GroupDescriptorFile 1
>
> Title ParietalWMH_age_gender_APOe_EC_left
>
> MeasurementName long.thickness-spc
>
> Class APOE_statusNO-genderF
>
> Class APOE_statusYES-genderF
>
> Class APOE_statusNO-genderM
>
> Class APOE_statusYES-genderM
>
> Variables Parietal_WMH age_years Avg_ECthickness
>
> Input W38284_base APOE_statusNO-genderF 0.732010 85.830000 3.125000
>
> .. (only listing the 1^st Input line here)
>
> My contrast file (C.dat) looks like below:
>
> 0 0 0 0 1 1 1 1 0 0 0 0 0 0 0 0
>
> And I’m trying to find p-values for these variables’ associations w/
> thickness: APOE status, gender, Parietal WMH, Age, Avg EC thickness.
>
Each contrast will have a sig file. But the command above will compute
the average significance, which really does not mean anything
>
> Thanks so much again for all the help!
>
> Batool
>