For further clarification, what are the main differences between the ' BrainSegVol' and eTIV'.
I understand the eTIV is determined from amount of scaling in the talariach transformation file and is not a voxel count. Does it include extra axial CSF?
BrainSegVol is total aseg/aparc voxel count but does not include brainstem or extra-axial /sulcal CSF, correct?
Jim
-----Original Message----- From: freesurfer-bounces@nmr.mgh.harvard.edu [mailto:freesurfer-bounces@nmr.mgh.harvard.edu] On Behalf Of Douglas N Greve Sent: Monday, September 11, 2017 2:59 PM To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Normalizing volumes
You can look here for what stats are available
https://surfer.nmr.mgh.harvard.edu/fswiki/MorphometryStats
There is no one method that is considered the gold standard. Each will represent a different hypothesis to test. Eg, if you use whole brain volume, then you will be looking at changes with respect to whole brain atrophy. If you use eTIV, the whole brain atrophy will be included in your measure
On 09/11/2017 01:12 PM, Alexopoulos, Dimitrios wrote:
Hi,
We running FS 5.3 analyses on 2 cohorts (control vs. malnourished adolescents) and I was wonderful what FS measure would be most accurate for normalizing the volumes.
(i.e total GM, total WM, suparatentorial, etc). The eTIV measures are significantly different between the cohorts.
Is eTIV the best way to normalize or perhaps BrainSegVol?
What FS measure gives you total brain volume?
Jim
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