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Dear Douglas,
Do you mean doing a paired analysis ( https://secure-web.cisco.com/1--BRKGsmqZ1L0g96_9NSyRbYR4I8YBmT3G8PQ1YzWvyN-a...
Thank you very much
Kind regards,
Agurne
El lun, 28 mar 2022 a las 9:18, Agurne Sampedro Calvete (< a.sampedro@deusto.es>) escribió:
Dear Douglas,
Do you mean calculate a type of change score (e.g. time2 minus time1) and then compare the differences between the two groups? How can I calculate the difference between the two time points? Thank you very much.
Best regards,
Agurne
El dom, 27 mar 2022 a las 23:07, Douglas N. Greve (dgreve@mgh.harvard.edu) escribió:
Probably the easiest thing to do since you have only two time points is to compute the difference between the two, then just do a simple group analysis where you include the covariates that you want.
On 3/23/2022 10:00 AM, Agurne Sampedro Calvete wrote:
External Email - Use CautionDear FreeSurfer experts,
I am doing a repeated measures ANOVA 2x2 (2 groups and 2 time points) and I would like to include in the analysis a covariate that is constant over the 2 times (e.g., baseline medication). I would like to see a "group x time x covariate" interaction.
What should the design look like? I know that without covariate the design is as follows:
GroupDescriptorFile 1
Class Subject1
Class Subject2
Variables Tp1vsTp2.Group1 Tp1vsTp2.Grroup2
Input Subject1_time1 Subject1 1 0
Input Subject1_time2 Subject1 -1 0
Input Subject2_time1 Subject2 0 1
Input Subject2_time2 Subject02 0 -1
Design matrix:
1 0 1 0
1 0 -1 0
0 1 0 1
0 1 0 -1
Contrasts (.mtx files): Tp1vsTp2.Group1 0 0 1 0 Tp1vsTp2.Group2 0 0 0 -1 Interaction (timexgroup) 0 0 1 -1
However, I do not know how I could include the interaction with that covariate.
Thank you very much in advance.
Kind regards,
Agurne
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