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Dear Wayne, We have an idea of what the problem might be and will look into it soon. Cheers, /Eugenio
-- Juan Eugenio Iglesias ERC Senior Research Fellow Translational Imaging Group University College London http://www.jeiglesias.com http://cmictig.cs.ucl.ac.uk/
From: freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Wayne Su waynewsu@gmail.com Reply-To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu Date: Wednesday, 2 May 2018 at 18:39 To: "freesurfer@nmr.mgh.harvard.edu" freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] kvlGEMSMatlab error: search direction is not a descent direction
External Email - Use Caution Hello FreeSurfer Developers,
I'm attempting to run longitudinal segmentation of hippocampal subfields by using the development version of FreeSurfer, but for some of my subjects I get the following error:
******************* Global iteration 3 *******************
***** Estimating subject-specific atlas ***** L-BFGS Verbose: 0 MaximalDeformationStopCriterion: 1e-10 LineSearchMaximalDeformationIntervalStopCriterion: 1e-10 MaximumNumberOfIterations: 1000 BFGS-MaximumMemoryLength: 12 Subject atlas deformation, step 1 of 400 Did one deformation step of max. 0.38685 voxels in 7.733 seconds
minLogLikelihoodTimesPrior =
1.0297e+05
Subject atlas deformation, step 2 of 400 Error using kvlGEMSMatlab /autofs/space/panamint_005/users/iglesias/software/freesurfer/GEMS2/kvlAtlasMeshDeformationOptimizer.cxx:327: itk::ERROR: AtlasMeshDeformationLBFGSOptimizer(0x2b53b9427df0): search direction is not a descent direction!
Error in kvlStepOptimizer (line 11) Error in SegmentSubfieldsT1Longitudinal (line 1169)
Does anyone have any thoughts on how to trouble-shoot this one?
1) FreeSurfer version: freesurfer-x86_64-unknown-linux-gnu-dev-20180426 2) Platform: CentOS Linux release 7.4.1708 (Core) 3) uname -a: Linux bcmhari-hpc12 3.10.0-327.el7.x86_64 #1 SMP Thu Nov 19 22:10:57 UTC 2015 x86_64 x86_64 x86_64 GNU/Linux
Thanks, Wayne