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I have used both CAT12 and Freesurfer to segment a particular brain scan and I get completely different volumes.
CAT12 (cc) Freesurfer 7.3.2 (cc) Left Cerebral White Matter volume(cc): 209 Left hemisphere cerebral white matter volume 242 Left Cerebral Cortex volume(cc): 444 Left hemisphere cortical gray matter volume 269 Left Lateral Ventricle volume(cc): 28 Left-Lateral-Ventricle 43 Right Cerebral White Matter volume(cc): 208 Right hemisphere cerebral white matter volume 242 Right Cerebral Cortex volume(cc): 440 Right hemisphere cortical gray matter volume 270 Right Lateral Ventricle volume(cc): 20 Right-Lateral-Ventricle 28 Total 1350 Total 1095 Total volume (cc): 1618.09 Brain Segmentation Volume 1309 Estimated Total Intracranial Volume 1852
What could be causing this difference?
The brain scan was done with MPRAGE protocol with 176x256x256 voxels of size 1mmx0.976mmx0.976mm
Which one is correct?
The scan is of a normal adult male aged 62 with chronic migraine.
Michael McLaughlin,