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Dear expert I am trying to calculate LGI for a subject. Now with some of your suggestions it runs, but after one hour and half it gives me this errors remeasuring lGI value for vertex iV = 29501. It may take a few minutes.WARNING -- Problem for vertex iV = 29501, lGI value is aberrantly high (lGI=42.4705)......lGI computation will be stopped. This may be caused by topological defects, check mris_euler_number on the pial surface. ERROR: compute_lgi did not create output file '/Applications/freesurfer/subjects/bianchi/surf/tmp-mris_compute_lgi-lh.pial/lh.pial_lgi.asc’! I think that is a problem of my file, someone knows a way to fix it? Thanks Lorenzo