Hi list, I'm not sure that the files reported below are correct to assess the longitudinal difference between T1 and T2.Please, could you check it? The result which I have obtained bu running mri_glmfit is too strange.ThanksBest regardsStefano 1) PAIRWISE.fsgd file-------------------GroupDescriptorFile 1Class subj1Class subj2...Class subjNVariables TP1-vs-TP2Input subj1_tp1 subj1 1Input subj1_tp2 subj1 -1Input subj2_tp1 subj2 1Input subj2_tp2 subj2 -1...Input subjN_tp1 subjN 1Input subjN_tp2 subjN -1---------------------------- 2) mean.mtx1 1 ... 1 0------------------------------3) tp-effect.mtx0 0 ... 0 1------------------------------4) mri_glmfit --glmdir PAIRWISE --y ces.nii.gz --wls cesvar.nii.gz --surface fsaverage rh --nii.gz --fsgd PAIRWISE.fsgd doss --C mean.mtx --C tp-effect.mtx