Hi Michael,
I think you should be fine with option 1. Just make sure that all cross are run with the same version (5.1). It is a little more complicated to keep track of things, but there should be no bias. That way you don't have to worry about edits.
If you only have very few edits, I would do the clean thing an re-run all data from scratch with 5.3 manually transferring edits only where needed.
Best, Martin
On Jul 9, 2013, at 3:01 PM, "Harms, Michael" mharms@wustl.edu wrote:
Hi guys, We have some longitudinal scans in which the time1 (T1) scans were processed with FS 5.1, and the T2/T3 scans haven't been processed yet.
I'm trying to assess whether the differences between FS 5.1 and 5.3 warrant us re-running the T1 scans under FS 5.3. I see two possible options:
Process all "cross-sectional" runs under FS 5.1. i.e., we already have T1 under FS 5.1, so do the cross-runs of T2/T3 under 5.1 as well. (I'm assuming that it wouldn't be desirable to have a mix of versions at the cross-sectional stage). Then switch to using FS 5.3 for creating the template (-base) and longitudinal (-long) data.
Re-process the cross-sectional scans for T1 using FS 5.3, and do everything with FS 5.3.
Do you have any reason to expect relevant differences in the final -long output between these two approaches? And, if approach (2) is necessary, do we need to re-run the T1 through FS 5.3 with the "-clean" flag? i.e,. if we were to re-run the cross-sectional version of the T1 scan using FS 5.3, but keeping previous edits, would that potentially bias the T1 scan in some fashion, since the T2/T3 scans will be run fresh in FS 5.3 without any prior manual edits?
thanks, -MH
-- Michael Harms, Ph.D.
Conte Center for the Neuroscience of Mental Disorders Washington University School of Medicine Department of Psychiatry, Box 8134 660 South Euclid Ave. Tel: 314-747-6173 St. Louis, MO 63110 Email: mharms@wustl.edu
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