Good afternoon; I am hoping you can help me answer a pretty quick & easy question…. I am trying to identify the best MRI protocol to use for Freesurfer analysis… When I look at the FAQ: Data Requirements The processing procedures for the creation of cortical models require good quality T1 weighted MRI data, such as a Siemens MPRAGE (examples of appropriate Siemens scanner protocols) or GE SPGR sequence with approximately 1mm3 resolution (although a variety of quality data sets can be processed with additional manual intervention). Thickness should not exceed 1.5mm (~1mm^3 is ideal). The protocols specified for the ADNI project are excellent examples to follow. The best FreeSurfer processing results come from scans having excellent gray/white matter contrast. The link to the ADNI project protocols is broken…I think that they should be here: http://adni.loni.usc.edu/methods/documents/mri-protocols/ Thanks Douglas