[Freesurfer] FA map registration to T1

Hello FreeSurfer Developers,

I am registering FA maps to T1 for a group of subjects with MS and in many cases the registration is poor for the anterior corpus callosum (attached), cerebellum, pons, and temporal lobe. I am using the following commands (FreeSurfer version 6.0):

bbregister \ --dti \ --reg diff2T1_reg.dat \ --mov eddy_corrected_b0.nii.gz \ --s subject_temp

mri_vol2vol \ --mov dtifit_FA.nii.gz \ --targ orig.mgz \ --o FA2T1.nii.gz \ --reg diff2T1_reg.dat

Do you have any suggestions for improving this registration?

Thank you, Andrew

Andrew Russo Clinical Research Coordinator Multiple Sclerosis Imaging Lab Massachusetts General Hospital 149 13th Street | Boston, MA 02129 617-726-7531