Dear Doug,
Many thanks for your answers.
- The bug was related to how the measures were converted to standard
space - I?d like to therefore confirm that when doing surface/vertex-based analyses, it is not necessary to use total brain volume as a covariate (whereas it is for ROI-based analyses).
This question has nothing to do with the bug. People generally use ICV or total brain volume when exploring cortical volume or surface area, but it is inappropriate for thicknss studies doug
Regarding the last point (which indeed has nothing to do with the bug, sorry for having given the impression that I thought that it did), why would one control for total brain volume in doing vertex-based analyses when the vertex-based measures are computed in standard space? I realize that this has to be done for ROI analyses since these measures are in native space.
Thanks again, and best, Narly.