Hi Adam
I don't think we know. It's probably ok, but you'll just have to try it out
Bruce On Mon, 29 Feb 2016, Adam Martersteck wrote:
Hi Freesurfer users,
I have a question about using the N3 algorithm twice for processing ADNI data:
Is it okay for data to have undergone the ADNI N3 correction (Boyes et al. 2008 http://www.ncbi.nlm.nih.gov/pubmed/18063391) AND then pushed through the Freesurfer pipeline and undergo FS N3 correction (Zheng, Chee, and Zagorodnov 2009 http://www.ncbi.nlm.nih.gov/pubmed/19559796)?
The problem stems from the fact that recent ADNI data has either undergone gradient warping correction (http://www.ncbi.nlm.nih.gov/pubmed/16300968) AND N3 correction or no corrections at all. The optimal solution would to have just been able to download the grad warp’d data and push that through.
Thanks for any thoughts! Adam