Hello, Freesurfer experts:
I found to report subcortical volumetric measure, ie, the volume of amygdale, people tend to use icv as a control variable. Is there any corresponding measure to correct the cortical thickness/area/volume results from autorecon3. Because we have priori hypothesis of hemisphere dichotomy of cortical structures, we need some control variable for each hemisphere. We want to use an overall measure for each hemisphere as a control variable. For example, to measure the group differences on rh_paracentral_thickness, we will use the rh_whole_thickness as a contral variable (which is the sum of the thickness measures of all the ROIs in the right hemisphere produced by Freesurfer). Similarly, to measure the group differences on rh_paracentral_area and rh_paracentral_volume, we will use the rh_whole_area and rh_whole_area as a contral variable respectively. Is this a valid approach to report our results?
Thanks a lot!
Karl