You can look here for what stats are available
https://surfer.nmr.mgh.harvard.edu/fswiki/MorphometryStats
There is no one method that is considered the gold standard. Each will represent a different hypothesis to test. Eg, if you use whole brain volume, then you will be looking at changes with respect to whole brain atrophy. If you use eTIV, the whole brain atrophy will be included in your measure
On 09/11/2017 01:12 PM, Alexopoulos, Dimitrios wrote:
Hi,
We running FS 5.3 analyses on 2 cohorts (control vs. malnourished adolescents) and I was wonderful what FS measure would be most accurate for normalizing the volumes.
(i.e total GM, total WM, suparatentorial, etc). The eTIV measures are significantly different between the cohorts.
Is eTIV the best way to normalize or perhaps BrainSegVol?
What FS measure gives you total brain volume?
Jim
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