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Dear FreeSurfer experts:
I am working on a manual for my lab and I would like to clarify the two points below (to which I couldn’t find answers in the online FS content available):
* When editing the wm.mgz fails, can control points (CPs) be used to correct pial errors cause by lesions (e.g., perivascular spaces, microbleeds, WMH). I understand the FS tutorial recommends against this, however at times it seems that only editing the wm.mgz will not be sufficient (Figure 1 below)
* Should white matter voxels with 0 intensity in the wm.mgz (inside the white surface) be filled in, even when these voxels do not affect white matter surface segmentation whatsoever? (Figure 2 below).
* Would the cerebral white matter volumetric data (wmparc.stats) be affected by these 0 intensity voxels?
Thanks so much for you help! Nárlon Cássio
Nárlon Cássio Boa Sorte Silva PhD (He, Him, His) CIHR and MSFHR/PARF Postdoctoral Research Fellow Aging, Mobility, and Cognitive Health Lab Djavad Mowafaghian Centre for Brain Health Department of Physical Therapy, Faculty of Medicine University of British Columbia Vancouver, Canada Twitter: @BoaNarlon [cid:0757C5B4-5E01-42A4-8BE6-6C5779C2D024][cid:E4FD3068-0778-4057-850B-40E9EB3318C8]
