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Good afternoon,
We want to find the functional areas where each electrode is located in patients. At present, we are finding the electrode RAS coordinates manually using CT-MRI co-registration. We are then manually searching for these locations in Freeview using the aparc.a2009s+aseg ATLAS (generated during MRI reconstruction) on top of MRI volume. This is giving us the exact anatomical/functional area where the electrode belongs. However, this is a very tedious and time-consuming process and we need to do this for many patients. We were wondering if there is 1. A way to automate this process by possibly entering all coordinates and using the LUT and atlas files to get the areas easily for all points.
2. More importantly, could you tell us how to establish a method where we can dump the anatomical region coordinates to a file, and then find the nearest functional area to a particular electrode automatically? For example, if a point lies in a white matter area, can we implement a process to find which functional area (gray matter region, or say hippocampus for example) lies CLOSEST to this electrode point in the white matter region. Can we implement this automated process in an efficient manner for all the points at once? We usually have anywhere between 140 -170 sets of coordinates for each patient, and doing this by hand on freeview is not practical. Instead of finding where exactly all the points lie, we would like to create a 'table' of all anatomical areas and then find out which area of relevance lies closest to a particular point.
Thank you Sparsh Jain