FS requires a T1-like contrast. I don't think that there is much you can do with DWI, and we would not support it if you were able to get it to run
On 3/24/2020 11:50 AM, Yixin Ma wrote:
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I was trying to use the average of DWI images (isoDWI) to run recon-all, and it didn't work. I understand that FreeSurfer can only take a T1-weighted image for now. But how hard would it be to modify the code by myself to make it work? If it works, how accurate do you think it would be to run FreeSurfer on isoDWI?
All the best and thank you for your help,
Yixin
Message: 8 Date: Fri, 13 Mar 2020 18:44:18 -0400 From: "Douglas N. Greve" <dgreve@mgh.harvard.edu mailto:dgreve@mgh.harvard.edu> Subject: Re: [Freesurfer] FreeSurfer Cortical Parcellation using isoDWI image only? To: <freesurfer@nmr.mgh.harvard.edu mailto:freesurfer@nmr.mgh.harvard.edu> Message-ID: <14b89d9d-130f-08f0-d593-71f2cdef3107@mgh.harvard.edu mailto:14b89d9d-130f-08f0-d593-71f2cdef3107@mgh.harvard.edu> Content-Type: text/plain; charset="utf-8"
you are trying to run a DWI image through recon-all? Sorry, it can only take T1w right now
On 3/12/2020 3:28 PM, Yixin Ma wrote:
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Hi Freesurfer experts,
I'm writing to ask if it's possible to run FreeSurfer Cortical Parcellation by just using the isoDWI image. If it's possible, it will reduce the scan time and avoid misregistration between T1 and DWI.
I started from just input the masked isoDWI (mask generated from MRtrix3) for -reconall command, and attached is a screenshot of the image of NU.mgz, which shows a clear delineation of WM/GM matter. So I think it's promising, although the recon-all stopped because of the wrong contrast. My ideas on tackling this problem are:
- generate a corresponding "fake" T1-weighted image by
either?adjusting the value directly or using a brain Atlas and deformable registration to create one. 2) Tweak some parameters in FreeSurfer.
Any suggestions or comments on my ideas are appreciated.
Thank you very much and all the best,
Yixin Ma
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