Hi Kelly,
it's a bit of an open question what the relationshop between thickness and icv is. It's probably not linear, maybe icv^(1/3)?
cheers Bruce
On Fri, 28 May 2010, Kelly Silva wrote:
Hello,
I'm doing regression analyses with cortical thickness at the level of voxel. Should I correct the total GM volume by introducing this parameter as a confounding variable? Shoud I include the intracranial volume as an additional nuisance variable? If positive, I assume that these variables can only be introduced as covariates if they differ between groups. Am I correct?
I saw in one message that we should not corret for thickness. Why not?
Thanks in advance and best regards, Kelly