I have processed more that 600 brains with both versions in the last weeks and the only difference I'm seeing between version 5.2.0 and 5.1, besides the obvious new features, is processing time.
Version 5.2 is 10% faster than 5.1 in an Amazon EC2 instance.
Besides that there's no visible difference in terms of cortical thickness, volumes, etc.
If you have access to computer resources to spare you can run recon-all of both versions in some well known database of images and do a more formal test.
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On Wed, Apr 10, 2013 at 8:11 AM, Yang, Daniel yung-jui.yang@yale.eduwrote:
Dear FreeSurfer Experts and Users,
Did anyone find similar things using FS 5.2 (please see my previous post below)? That is, FS 5.2 is including more non-cortical "black spaces" within pial surfaces, compared to FS 5.1?
I'm not interested in nitpicking but I feel this is a rather serious issue, so I would like to raise it again before it's completely forgotten.
At the meantime I keep receiving Emails from people asking me this issue.
Thanks! Daniel
-- Yung-Jui "Daniel" Yang, PhD Postdoctoral Researcher Yale Child Study Center New Haven, CT (203) 737-5454
On 3/19/13 7:07 AM, "Yang, Daniel" yung-jui.yang@yale.edu wrote:
Posting one of the brains.
https://yalesurvey.qualtrics.com/SE/?SID=SV_ddwW7I9yMQuCtPn
It seems to me that neither version is perfect; however, 5.2.0 is capturing more "black spaces" in the region I'm looking at.
It's in the right hemisphere, TAL coordinate about ~ (44, -46, 20).
Given that the correlation between 5.1.0 and 5.2.0 is r = .33 in the region I examined with my samples, it's not a systematic "predictable" bias.
Any solution?
-- Yung-Jui "Daniel" Yang, PhD Postdoctoral Researcher Yale Child Study Center New Haven, CT (203) 737-5454
On 3/18/13 6:27 PM, "Matt Glasser" matt@ma-tea.com wrote:
Do the surfaces look correct in these regions? You might post some screenshots of subjects who have a big difference between 5.1 and 5.2 with the 5.1 and 5.2 white and pial surfaces on volume slices that highlight the difference. Without this kind of info, its hard to know which was more correct, 5.1 or 5.2.
Peace,
Matt.
On 3/18/13 5:13 PM, "Ritobrato Datta" ridatta@mail.med.upenn.edu
wrote:
I concur. I have seen similar results in primary visual cortex from ~40 subjects. While fs 5.1 estimated mean thickness in the range of 1.5 to 1.9 in V1, fs 5.2 is giving me V1 thickness in the range of 2 to 2.3.
Ritobrato Datta, Ph.D. Post Doctoral Researcher Department of Neurology University of Pennsylvania School of Medicine 3rd Floor, Room 312 3710 Hamilton Walk (Goddard Laboratories) Philadelphia, PA 19104-6241 email - ridatta@mail.med.upenn.edu
----- Original Message ----- From: Daniel Yang yung-jui.yang@yale.edu To: freesurfer@nmr.mgh.harvard.edu Sent: Mon, 18 Mar 2013 17:44:44 -0400 (EDT) Subject: [Freesurfer] Very different results between 5.1.0 and 5.2.0
Dear FreeSurfer Experts,
I ran FreeSurfer 5.1.0 and FreeSurfer 5.2.0 on identical set of 161 subjects, and I'm interested in rh_superior_temporal_sulcus_thickness in particular.
Previously, the mean thickness is 2.24 mm in 5.1.0; now it is 3.28 mm in 5.2.0. They are significantly different, t(160) = 56.71.
The correlation between the two versions is r = .33
Is this something possible?? I can't see what went wrong in my procedures.
Thanks! Daniel
-- Yung-Jui "Daniel" Yang, PhD Postdoctoral Researcher Yale Child Study Center New Haven, CT (203) 737-5454
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